Truth And Nonviolence Will Never Be Destroyed Those Words Spoken By Ma

" Truth and nonviolence will never be destroyed" those words spoken by Mahatma Gandhi describe the true essence of his character. He was a man who unlike others decided to use nonviolence as a means of getting what he wanted. His different approach is what ultimately led to his rising popularity and strong success. Not only did Gandhi almost single-handedly free India and its five hundred million people from their long subjection to the British Empire, but he did so without raising an army, without firing a gun or taking a hostage, and without ever holding a political office. Mohandas Karamch and Gandhi was born on October 2, 1869, in Porbandar, near Bombay. Gandhi's family belonged to the merchant class called Vaisya. His father had been the Prime Minister of several small native states. At the young age of 13 Gandhi was married. The marriage was arranged with Kasturbai Makanji. At age 19 Gandhi set out to study abroad. He studied law at the University College in London. He found that there he was often looked down upon for being Indian. In 1981 Gandhi returned to India. At Natal he was the first so-called "colored" lawyer admitted to the Supreme Court. He then built a large practice. Gandhi soon became interested in the problems faced by fellow Indians who came to South Africa as laborers. He noticed how they were treated as inferiors. In 1894 he founded the Natal Indian Congress to agitate for Indian rights. In 1899, during the Boer War, he raised an ambulance corps and served the South African government. In 1906 Gandhi began his peaceful revolution. He announced that he would go to jail or even face death before he would obey an anti-Asian law. He never wavered in his unshakable belief in nonviolent protest and religious tolerance. Thousands of Indians joined him in the civil disobedience campaign. Twice Gandhi was imprisoned. He worked to reconcile all classes and religious sects, especially Hindus and Muslims. Gandhi became the international symbol of a free India. He lived a spiritual and ascetic life of prayer, fasting, and meditation. His union with his wife became, as he himself stated, that of brother and sister. Refusing earthly possessions, he wore the loincloth and shawl of the lowliest Indian and subsisted on vegetables, fruit juices, and goat's milk. Indians revered him as a saint and began tocall him Mahatma (great-souled), a title reserved for the greatest sages. Gandhi's advocacy of nonviolence, known as ahimsa (non-violence), was the expression of a way of life implicit in the Hindu religion. By the Indian pract ice of nonviolence, Gandhi held,Great Britain too would eventually consider violence useless and would leave India. When Muslim and Hindu compatriots committed acts of violence, whether against the British who ruled India, or against each other, he fasted until the fighting ceased. In 1919 he became a leader in the newly formed Indian National Congress political party. In 1920 he launched a noncooperation campaign against Britain, urging Indians to spin their own cotton and to boycott British goods, courts, and government. This led to his imprisonment from 1922 to 1924. In 1930, in protest of a salt tax Gandhi led thousands of Indians on a 200-mile march to the sea to make their own salt. he was then jailed again . This was called the "Salt March." In 1934 he retired as head of the party but remained its actual leader. Slowly Gandhi became to realize that that India would receive no real freedom as long as it remained in the British Empire. Gandhi's victory came in 1947 when India won independence. The victory was not a military victory, but a triumph of human will. The subcontinent split into tw o countries Hindu India and Muslim Pakistan. The last two months of his life were spent trying to end the appalling violence which ensued, leading him to fast to the brink of death, an act which finally quieted the riots. On Jan. 30, 1948, while on his way to prayer in Delhi, a Hindu, Nathuram Godse killed Gandhi. He had been maddened by Gandhi's efforts to reconcile Hindus and Muslims. Three shots from a small automatic pistol were which led to his final

Explore the Sombrero Galaxy

Explore the Sombrero Galaxy Way out in the direction of the constellation Virgo, some 31 million light-years from Earth, astronomers have found a most unlikely looking galaxy that is hiding a supermassive black hole at its heart. Its technical name is M104, but most people refer to it by its nickname: the Sombrero Galaxy. Through a small telescope, this distant stellar city does look a bit like a big Mexican hat. The Sombrero is incredibly massive, containing the equivalent of 800 million times the mass of the Sun, plus a collection of globular clusters, and a broad ring of gas and dust. Not only is this galaxy huge, but its also speeding away from us at a rate of a thousand kilometers per second (about 621 miles per second). Thats very fast! What is That Galaxy? At first, astronomers thought the Sombrero might be an elliptical-type galaxy with another flat galaxy embedded within it. This is because it did look more elliptical than flat. However, a closer look revealed that the puffy shape is caused by a spherical halo of stars around the central area. It also has that huge dust lane that contains starbirth regions. So, its most likely a very tightly wound spiral galaxy, the same type of galaxy as the Milky Way. How did it get that way? Theres a good chance that multiple collisions with other galaxies (and a merger or two), have changed what may have been a spiral galaxy into a more complex galactic beast. Observations with the Hubble Space Telescope and the Spitzer Space Telescope have revealed a lot of detail in this object, and theres a lot more to learn! Checking Out the Dust Ring The dust ring that sits out in the brim of the Sombrero is very intriguing. It glows in infrared light and contains most of the star-forming material of the galaxy - such materials as hydrogen gas and dust. It completely encircles the central core of the galaxy, and appears pretty wide. When astronomers looked at the ring with the Spitzer Space Telescope, it appeared very bright in infrared light. Thats a good indication that the ring is the central starbirth region of the galaxy. Whats Hiding in the Nucleus of the Sombrero? Many galaxies have supermassive black holes at their hearts, and the Sombrero is no exception. Its black hole has more than a billion times the mass of the Sun, all packed away into a tiny region. It appears to be an active black hole, eating up material that happens to cross its path. The region around the black hole emits a tremendous amount of x-ray and radio waves. The region extending out from the core does emit some weak infrared radiation, which could be traced back to heating activity fostered by the presence of the black hole. Interestingly, the core of the galaxy does appear to have a number of globular clusters swarming around in tight orbits. There may be as many as 2,000 of these very old groupings of stars orbiting the core, and may be related in some way to the very large size of the galactic bulge that houses the black hole. Where is the Sombrero? While astronomers know the general location of the Sombrero Galaxy, its exact distance was only recently determined. It seems to be about around 31 million light-years away. It does not travel the universe by itself, but does appear to have a dwarf galaxy companion. Astronomers are not quite sure if the Sombrero is actually part of a grouping of galaxies called the Virgo Cluster, or may be a member of a smaller associated group of galaxies. Want to Observe the Sombrero? The Sombrero Galaxy is a favorite target for amateur stargazers. It takes a little doing to find it, and it does require a good backyard-type scope to view this galaxy. A good star chart shows where the galaxy is (in the constellation Virgo), halfway between Virgos star Spica and the tiny constellation of Corvus the Crow. Practice star-hopping to the galaxy and then settle in for a good long look! And, youll be following in a long line of amateurs who have checked out the Sombrero. It was discovered by an amateur in the 1700s, a guy by the name of Charles Messier, who compiled a list of faint, fuzzy objects that we now know are clusters, nebulae, and galaxies.

Benefits of breast feeding and natural birthing techniques Research Paper

Benefits of breast feeding and natural birthing techniques - Research Paper Example On the other hand, nutrients in mother’s milk also help to prevent the spread of childhood infectious and noninfectious diseases. This means that the benefits of breastfeeding are limitless, and it is a momentous act a mother does to determine the present and future health of a child (Department of Health and Human Service Office on Womens Health , 2003). In the current world, breastfeeding has been considered not to be beneficial, and that infants can be fed formula milk and survive. I disagree with this and can say that formula milk will never have similar vitamins and nutrients that are in the human milk even if vitamin, minerals and supplements included in formula milk, additionally, breastfeeding is also beneficial to mothers. Firstly, breastfeeding prevents the high risks of infectious diseases on children. Research has shown that breast milk prevent children against infectious diseases like lower and upper respiratory infections than formula milk. These infections are caused by lack of immunity and antibacterial that are present in human milk, hence most children affected with these infections are those fed formula milk. Latest research has also indicated that breastfeeding helps in preventing urinary tract infections. Secondly, breastfeeding is also beneficial to children who are born as a result of pre- mature births leading to children being born before they fully develop. The term that is usually used by most medics is neurodevelopment. Studies have indicated that breastfeeding contributes to cognitive development of infants whereby children who are breastfed develop faster than those fed formula milk. However, it reduces the death rate during early childhood. Studies have indicated that most death is common in formula fed infants because there is no interaction that takes place between mother and child when breastfeeding hence, mothers’ intelligence during breastfeeding also contribute to few SIDS

Applies the lesson to analyse a real world issue Assignment

Applies the lesson to analyse a real world issue - Assignment Example This phenomenon is not unique as during the Great Depression in 1930’s the world economy underwent a similar occurrence. According to Hazlitt (1946), there is a difference between economists; good economists and bad economists. The bad economists observe the direct impacts of proposed course, whereas the good one focuses on long and indirect consequence. Teiying economic to long term predictions is the foundations of a good economist and as Brux, (2005) predicted long term economic eventualities such as poverty marks such characteristics.   This argument cannot be further from the truth. Economists have always been grouped into different groups, but the world’s most prominent group is the Keynesian school of thought. Other economic schools of thoughts that have dominated academic thoughts throughout the 20th century and even the 21st century are the monetarist school of thought and the Harvard economic school of thought. According to the Keynesian school of thought, private capital investment decreased as a result of more capacity and the deficiency in good investment opportunities (Hetzel, 2012).   In fact, the concept of Secular Stagnation, a term coined by the Keynesian school of economics and it attributed the recession to inadequate capital investment hindering full employment of labour and other economic resources. Aptly referred to as the secular stagnation theory as articulated by the Keynesian school of economics, is a marketed different from the notion propagated by the monetarist school of economics. According to the monetarist theorists the recession was as a result of the tendency of the rate of profit to decrease, and as such businesses will block investments in manufacturing plants with a decreasing rate of return. Theorists have provided different arguments on the phenomenon of low economic growth, and especially that regards the same that was realized in the industrialized

Multi line regression Statistics Project Example | Topics and Well Written Essays - 1250 words

Multi line regression - Statistics Project Example atly depends on statistics in order to determine how well a country is doing in terms of trading with the relevant partners and in enhancing economic growth. In this task, the chosen dependent variable was the United States of America exports, the dependent variables selected are; oil prices, USA car prices and technological product prices. It is assumed that the selected independent variables have a direct relationship with the dependent variable. For instance, car prices will determine if the exports of the same will be higher, especially when compared to prices of cars from other countries such as Japan. In order to understand how the independent variables impact on the dependent variable, multiple regression analysis is usually utilized. Regression is a statistical analysis that is used to evaluate the association or relationship between continuous dependent and continuous independent variable (Chatterjee & Simonoff, 2013). Usually the regression analysis helps establish a number of issues such as if a relationship exists between variables, the strength of the association, the structure or form of the relationship, as well as help in predicting the values of the dependent variable and controlling for other dependent variables. This makes regression superior to correlation analysis. Ideally, regression coefficients depict the mean, variance or change variables under investigation variable for one unit of change in the predictor variable while holding other predictor variables constant in the same model. With regards to coefficients above, it is evident that when oil prices and technical product prices are held constant, the amount of exports will increase by 6.94, when car prices, and technical product prices are held constant, then exports will increase by 4.27 and lastly, when car prices and oil prices are held constant, exports will reduce by -0.52. R-square value stood at 0.9472. Coefficient of determination adjusted for the degree of freedom denoted as

Analytical Approaches in the Pharmaceutical Industry

Analytical Approaches in the Pharmaceutical Industry Miracles do happen and chances of happening such events are rare. Scientific discoveries have also seen such miracles. The approach and efforts required in scientific happenings are based on basic principles. The mode of application of these established principles differ from one stream to another stream of scientific disciplines. The principle of chemistry and physics are amalgamated to give rise to number of measuring devices. These devices are further restructured to suit application. Analytical chemistry can be defined as the science and art of determining the composition of materials in terms of their elements or compounds contained1 in it. Qualitative analysis gives useful details from which functional groups, structural features, atomic species or molecular species. Quantitative analysis gives numerical data in units i.e. percentage, parts per million, moles per liter etc. In above two types of analysis, the required data is obtained by measuring a physical property which is characteristically related to respective component of interest i.e. the analyte2. The most important aspect of analysis is quantitative analysis. The techniques of analytical chemist are of vital importance to the drug and pharmaceutical industries. Products are usually complex organic compounds or mixtures. Drugs prepared for human consumption requires strict standards of product quality be established and maintained. In past, methods of biological assay were often the only measure of product activity available. With the advent of modern instrumentation, techniques of analyst became more versatile and less time consuming, and quantitative analysis supplemented and sometimes replaced biological assay. In those instances where it is possible to establish a rigorous correlation between biological activity and chemical composition of product, analysis can be invaluable in controlling manufacturing operations as well as in determination of product purity and activity. It is noted that the progress and advancement of analytical chemistry depends to a greater extent upon an intelligent application of the fundamentals of physical chemistry and close relationship between physical and analytical chemistry. Recent rapid progress in physical methods of analysis, in many instances, resulted from pioneering investigations of scientists, principally physicists. In 1930 Willard recognized the demands being placed on analytical chemistry by rapid industrial progress. A parallel recognition of importance of analytical chemistry to industry occurred in Europe in same year. Churchill states that contribution of the analytical chemist to research program will be most effective if he is given the opportunity to participate while the program is being planned. In 1940s several direct reading quantitative spectrophotometers were reported. In these instruments the emitted spectral energy of certain chosen lines is transformed to a proportional electrical output by photomultiplier tubes. By suitable amplification and with appropriate recording devices, percentages of the constituents present are automatically recorded. The outstanding advantage of such equipment is its ability to reduce the time requirement for performing an analysis. New information made available by combining various tools of analytical chemist, has been described in several articles. The methods of analysis used to solve industrial problems may be classified as:- Fully developed, generally accepted methods of analysis. Generally accepted methods which are adapted to make them suitable for the problem. New methods which must be developed when available ones are not adequate. Industrial analysis is defined as the utilization of chemical and physical techniques for solving problems arising in industry. In some industrial processes it is desirable to obtain a very rapid or continuous analysis of a product or mixture. Considerable progress has been made in developing automatic method of analysis to fulfill this need. While it has not often been possible to automate entire procedures, from sampling to recording of results many examples of partly automated analytical operations can be cited. Factors pertinent to evaluation of analytical methods in each of these groups were discussed in the present section. A method of analysis is standard or accepted only in the sense that a number of analysts have judged it to be adequate for obtaining certain analytical information. Ideally, analyst views the standard method as a â€Å"best approach† rather than an obvious solution. If satisfactory results are obtained the method can be applied to the sample under consideration with some assurance that the experimental procedure is not at fault. The analyst himself should perform this part of work even if future measurements will be carried out by technicians or laboratory assistant. Only by performing the manipulation and observing the reaction can the analyst forming thoroughly acquainted with the details of an analytical procedure. The advisable method is when it appears to give satisfactory results, include consideration of interfering elements or compounds and determination of blank. While interferences which prevent a method from working properly are readily detected, those which produce a constant error in the analytical result are much more insidious and seldom apparent. Determination of a blank eliminates possible source of constant errors, such as contaminants in reagents and uncorrected background in instrumental measurements. In many standard methods the design and dimensions of the equipment are critical, particularly when properties of material rather than its composition is being studied. Many modification of an analytical method are possible and each problem or sample dictates the changes required to make the method effective. In some methods modification involves change in equipment or technique. For example, numerous spectrographic procedures have been developed for analyzing the metallic contaminants or additives in lubricating oils. Methods, which fail or suffer loss in sensitivity when certain interferences are present, may sometimes, need to be modified by introducing an additional step in the procedure which eliminates or deactivates the interfering element. Once a procedure has been adapted to a particular problem it may be evaluated in the same manner as a standard method. The usual precautions related to proper manipulation and standardizations, avoiding contamination and blank determinations must be observed. When problem is confronted which cannot be solved with established methods of analysis, it becomes necessary for analyst to create and develop new analytical procedures. This situation arises when any or all of the following factors are in effect. The substance sought has not previously been determined, when no methods are now available for all elements. The substance sought is a component of a mixture not previously analyzed. Any other element or compound present in a mixture may invalidate established methods of analysis by interference effects. Sometimes the component producing the interferences can be eliminated and a modified form of the original procedure can be used, as already described. Higher order of sensitivity is required when component sought is present in small quantity (mg). A method capable of analyzing in desired concentration range must be developed. Problems arising in industry are complicated by sample limitations. Often the sample is available in very small amounts and special techniques are required for gaining maximum information from a minimum quantity of material. Analysis must be non-destructive. At times it is required that the sample remain unaltered by the analytical procedure. For example compositional information on an expensive finished product is required, a non-destructive analytical method. Speed or time is critical requirement when conventional methods cannot complete an analysis within a prescribed time requirement, faster methods must be developed. Analytical Chemistry importance in different scientific areas: Importance of analytical chemistry in related scientific areas can be demonstrated by considering analytical chemistry’s impact on clinical analysis, and in pharmaceutical research and in quality control. Sensitive chemical and instrumental tests were advised in order to detect abnormal and normal components of body fluids. Blood and urine samples are determined for percentage of glucose, urea, nitrogen, protein, sodium, potassium, calcium, uric acid etc. Similarly, the quality of manufactured drug in tablets, solution and emulsion form must be carefully controlled in pharmaceutical industry, otherwise the drug can itself affect the therapeutic value. In other pharmaceutical studies, it is important to establish properties and therapeutic value of a drug before the drug is approved and made available to the public. Analytical Techniques: Few of medicinal products were still being analyzed by time-tested procedures of gravimetric and also titrimetric procedures. A wide diversity in different type of analytical techniques has been characteristic of assay methods for pharmaceutical products. Different analytical techniques were been employed for estimation of wide variety of components in the formulation:- Titrimetric and gravimetric method Colorimetric and UV spectrophotometric method Paper chromatography Preparative thin layer chromatography Column chromatography Ion-exchange chromatography Flame photometry and atomic absorption spectrometry. Variables in Quantitative Analysis: Inhomogeneity of the medicament Sampling error Preparation of samples such as extraction Precision, accuracy and ruggedness of the method Random error including that of the operator. Newer Analytical Techniques: As technology is developing, a number of new drugs are launched in the market and it is essential to develop new methods of analysis. It is necessary to do if; No analytical methods are available for a drug in official books such as pharmacopoeias. No literature reveals methods for estimation of drugs. Analytical method available only for single drug in a combined form of drug. No method reported for the estimation in biological fluids. NEED OF ANALYTICAL APPROACHES IN PHARMACEUTICAL INDUSTRY The pharmaceutical industry has always had in place a series of process controls which assures the integrity of the end product. â€Å"A simple way of looking at it is that the Food Drugs Act Regulations are merely an auditing mechanism to quantify that industry has sufficient process controls and documented procedures in place to ensure they are in complete control of every aspect related to drug manufacturing,† There are in essence, three pillars to drug manufacturing and distribution: 1. Quality Assurance (QA) 2. Good Manufacturing Practices (GMP) 3. Quality Control (QC) Quality Assurance is ensuring that you get what you pay for. It is the insurance policy for the manufacturer.† As a brief overview, the GMPs are part of Quality Assurance and ensure that drugs are produced consistently and are controlled at each and every step. QC is a part of Good Manufacturing Practices and is responsible for sampling and also for testing. It examines and ensures that all aspects of product from raw materials and integrity of the product itself to the packaging materials and insert, meet their specifications. It encompasses testing of the end product and all of its primary ingredients. QA covers documentation of all of the procedures that have taken place from start to finish of entire process. This, in combination with QCs sampling and testing, allows QA to ensure products integrity, purity and potency have not been compromised and it has satisfied all requirements. When QA is completed and satisfactory, the final step is permitted allowing a product to be r eleased for sale to the consumer. But, their job doesn’t stop here. Since Quality Assurance is responsible for assuring that final product is meeting quality, consistency and integrity for its intended use, it must also account for when the product leaves the manufacturing site. Thus, QA is also responsible for ensuring that appropriate arrangements have been made with distributors and warehouses to guarantee that the product is handled, stored and shipped in such a way that its quality is maintained for the duration of its approved shelf life. The overall time required for development of a pharmaceutical from Discovery Research through to the Regulatory Review Phase. There is clear evidence that this can in some cases take upwards of 15 years with costs reaching into millions of dollars. With this level of Research and Development investment, the industry has no intention of allowing a breakdown in final stages of manufacturing and distribution process. Therefore, before a product actually reaches market, QA involvement is also the key in the registration dossier preparation. A portion of this dossier contains a Master Production Document (MPD) which outlines exactly how the product will be manufactured. Within this MPD, a manufacturer defines clear specifications for all raw materials, packaging materials, in-process and finished product along with the sampling procedures and also Standard Operating Procedures (SOPs) related to critical processing. The issuing of a Notice of Compliance and a Drug Identification Number are contingent on a complete and acceptable Master Production Document. Then manufacturing license holders are also responsible for conducting an annual self-inspection and documenting their procedures and processes are in compliance with the requirements of the GMPs. If the manufactured product is stored in bottles (syrups), fabricating, packaging/labeling, importation, distribution, wholesale (Schedule C, D, F or G products) or testing of pharmaceutical products must first hold an Establishment License issued by Government. PRESENT STUDY: Development of new drugs, drug manufacturing is dependent on drug analysis. Pharmaceutical companies depend upon drug analysis quantitatively to conform that the raw materials used, in-process compounds and final products manufactured were meeting the required specifications. New drug formulations and new drugs were introduced into the market at increased pace compared to earlier days, as the technology is developed. These formulations and drugs were either new chemical entities or partial structural modifications of existing drugs or new dosage forms. Frequently, it happens that the new drugs inclusion in pharmacopoeias will be delayed because of several reasons. Hence these standards or the analytical methods for these drugs may not be available in pharmacopoeias. Hence it is essential to develop new methods of analysis for these drugs. Based on this, few combinations were selected for the present studies which were currently marketed from Anti Hypertensives17-22, Anti HIV23-35 and Non Steroidal Anti Inflammatory Drugs36-47. Amlodipine Besylate Telmisartan Lamivudine Zidovudine Thiocolchicoside Etoricoxib Literature survey was performed extensively and it was found that spectrophotometric methods were reported and also HPLC methods were reported for the determination of these drugs from their biological fluids. However, there were no reports found for their quantitation by HPLC methods from their formulations. Hence it is essential to develop newer rapid analytical methods3-16 on HPLC.

Circadian Rhythms: Experiment :: essays research papers

Circadian Rhythms: Experiment Circadian Rhythms are the times of day that you get either hungry, tired, or energetic. This paper is to describe an experiment that I have thought up that will test to see if circadian rhythms differ from people who perceive themselves as night-time people and people who perceive themselves as morning people. What is your hypothesis?   Ã‚  Ã‚  Ã‚  Ã‚  My hypothesis is that night-time people's circadian rhythms are extremely different than morning people's circadian rhythms. What population are you going to study? How will you sample this population?   Ã‚  Ã‚  Ã‚  Ã‚  Participants for my experiment will be ninety-nine undergraduate female students from Iowa State University. Prior to the experiment all participants will have to fill out a questionnaire. This questionnaire will primarily determine if they feel themselves as being either morning or night types of people. Subjects for my experiment will be randomly chosen from these questionnaires. I will select three night-time people and three morning-time people. I will then give each of them a journal. In this journal each subject will write in it the time that they become hungry, or the time that they became tired. They will do this for three days. At the end of the three days they will come back to my laboratory. They will then be put in an isolation booths. In one of the booths there will be a clock that doesn't have the right time on it. In another one there will be a window so that they can see where the sun is. In the third one there will be no windows and no clocks. All they would have is a light bulb in the ceiling. All the booths will have a bed and a bright red button on the far wall. The button will be for ringing. They will ring when they are tired, hungry, or need to use the facilities. My assistants and I will record when they become hungry and when they become tired. They will be in this room for three days. At the end of the three days my assistants and I will make sure that they are all right and can return to the world unharmed. What is your independent variable(s)? What is your dependent variable? How will you measure the dependent variable?   Ã‚  Ã‚  Ã‚  Ã‚  My independent variable will be one of the three that I give a clock and another one that I give a view of where the sun is. The dependent variable will be the one that will be completely isolated. Without sunlight they will not know what time it is and therefore not know when to become tired or hungry.